Oral Iron Therapy for Heart Failure With Reduced Ejection Fraction: Design and Rationale for Oral Iron Repletion Effects on Oxygen Uptake in Heart Failure.

@article{Lewis2016OralIT,
  title={Oral Iron Therapy for Heart Failure With Reduced Ejection Fraction: Design and Rationale for Oral Iron Repletion Effects on Oxygen Uptake in Heart Failure.},
  author={Gregory D. Lewis and Marc J. Semigran and Michael M. Givertz and Rajeev Kumar Malhotra and Kevin J. Anstrom and Adrian F. Hernandez and Monica R. Shah and Eugene Braunwald},
  journal={Circulation. Heart failure},
  year={2016},
  volume={9 5}
}
UNLABELLED : Iron deficiency is present in ≈50% of patients with heart failure and is an independent predictor of mortality. Despite growing recognition of the functional and prognostic significance of iron deficiency, randomized multicenter trials exploring the use of oral iron supplementation in heart failure, a therapy that is inexpensive, readily available, and safe, have not been performed. Moreover, patient characteristics that influence responsiveness to oral iron in patients with heart… CONTINUE READING