Oral Ibuprofen versus Intravenous Ibuprofen or Intravenous Indomethacin for the Treatment of Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-Analysis

@article{Neumann2012OralIV,
  title={Oral Ibuprofen versus Intravenous Ibuprofen or Intravenous Indomethacin for the Treatment of Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-Analysis},
  author={R. Neumann and S. Schulzke and C. B{\"u}hrer},
  journal={Neonatology},
  year={2012},
  volume={102},
  pages={15 - 9}
}
  • R. Neumann, S. Schulzke, C. Bührer
  • Published 2012
  • Medicine
  • Neonatology
  • Background: Pharmacological closure of patent ductus arteriosus (PDA) is commonly achieved by intravenous (IV) administration of ibuprofen or indomethacin. Occasionally, oral ibuprofen is used for PDA treatment although its efficacy and safety are unclear. Objectives: To systematically review randomized and quasi-randomized trials comparing oral ibuprofen with IV ibuprofen or IV indomethacin for closure of PDA in preterm infants. Methods: The standard search methods of the Cochrane Neonatal… CONTINUE READING

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    Paper Mentions

    INTERVENTIONAL CLINICAL TRIAL
    Patent ductus arteriosus or PDA is a blood vessel that connects the right and left side of the heart that usually closes after birth but remains open in some premature infants born… Expand
    ConditionsNeonate, Patent Ductus Arteriosus
    InterventionDrug

    References

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    A randomized controlled trial on the use of oral ibuprofen to close patent ductus arteriosus in premature infants
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