Oral Ibuprofen Interferes with Cellular Healing Responses in a Murine Model of Achilles Tendinopathy

@inproceedings{Bittermann2018OralII,
  title={Oral Ibuprofen Interferes with Cellular Healing Responses in a Murine Model of Achilles Tendinopathy},
  author={Adam Bittermann and Shuguang Gao and Sabah N. Rezvani and Jun Li and Katie J Sikes and John H. Sandy and Vincent M. Wang and Simon Jong-Koo Lee and George Winslow Holmes and Johnny Sn Lin and Anna Plaas},
  booktitle={Journal of musculoskeletal disorders and treatment},
  year={2018}
}
Background The attempted healing of tendon after acute injury (overloading, partial tear or complete rupture) proceeds via the normal wound healing cascade involving hemostasis, inflammation, matrix synthesis and matrix remodeling. Depending on the degree of trauma and the nature of the post-injury milieu, a variable degree of healing and recovery of function occurs. Post-injury analgesia is often achieved with NSAIDs such as Ibuprofen, however there is increasing evidence that NSAID usage may… CONTINUE READING
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