• Corpus ID: 41188335

Oral Glucose Tolerance Test ( OGTT ) in Normal Control and Glucose Induced Hyperglycemic Rats with Hedyotis leschenaultiana

@inproceedings{Sornalakshmi2016OralGT,
  title={Oral Glucose Tolerance Test ( OGTT ) in Normal Control and Glucose Induced Hyperglycemic Rats with Hedyotis leschenaultiana},
  author={DC Sornalakshmi and Tresina Soris and P. V. A. Lincy},
  year={2016}
}
ABSTACT The effect of ethanol extract of whole plant of Hedyotis leschenaultiana on Oral Glucose Tolerance was determined. Glibenclamide (600μg/kg) was used as reference drug for comparison. Ethanol extract of Hedyotis leschenaultiana whole plant was evaluated for Oral Glucose Tolerance Test (OGTT) in normal and alloxan induced diabetic rats. Blood glucose concentration was evaluated at 0, 30, 60, 90 and 120 minutes after treatment in both cases. The extract significantly (p < 0.001) reduced… 
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Phytochemical screening and establishment of antidiabetic potentiality of aqueous leaf extract of endangered plant Decalepis nervosa in alloxan induced diabetic rats
TLDR
The first report on the phytochemicals and therapeutic activity of AEDN leaf was established with potential antidiabetic activity by increased insulin secretion via enhanced peripheral glucose utilization mechanism.

References

SHOWING 1-10 OF 17 REFERENCES
Antidiabetic and in vitro antioxidant potential of Hybanthus enneaspermus (Linn) F. Muell in streptozotocin-induced diabetic rats.
Hypoglycaemic and antidiabetic activity of acetonic extract of Vernonia colorata leaves in normoglycaemic and alloxan-induced diabetic rats.
Effect of Cynoglossum zeylanicum (Vehl ex Hornem) Thunb. Ex Lehm on Oral Glucose Tolerance in rats
TLDR
Results suggest that the ethanol extract of Cynoglossum zeylanicum whole plant will be useful in the treatment of impaired oral glucose tolerance.
Evaluation of Traditional Indian Antidiabetic Medicinal Plants for Human Pancreatic Amylase Inhibitory Effect In Vitro
TLDR
Analysis of Ayurvedic Indian medicinal plants subjected to sequential solvent extraction revealed the presence of alkaloids, proteins, tannins, cardiac glycosides, flavonoids, saponins and steroids as probable inhibitory compounds.
Antidiabetic activity of Terminalia catappa Linn fruits.
Pancreatic beta cell regeneration – a novel antidiabetic mechanism of Pterocarpus marsupium roxb
TLDR
The drug XE effectively reversed the alloxan-induced changes in the blood sugar level and the beta-cell population in the pancreas and may offer a new hope to the diabetics in future.
Pancreas transplantation and diabetic complications.
  • L. Luzi
  • Medicine
    The New England journal of medicine
  • 1998
TLDR
It is reported that pancreas transplantation reverses the lesions of diabetic nephropathy in patients who have type 1 diabetes without uremia and who become normoglycemic after transplantation.
The effect of diabetes and insulin on liver glycogen synthetase activation.
  • A. H. Gold
  • Biology, Chemistry
    The Journal of biological chemistry
  • 1970
Oral hypoglycaemic plants in West Africa.
Recent Natural Products Based Drug Development : A Pharmaceutical Industry Perspective
TLDR
A number of important natural product-based drug developments in the past 10-15 years are summarized, mostly from the perspective of pharmaceutical industry, which have led to therapeutically useful agents either in current clinical use or in various stages of clinical trial.
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