Oral Contraceptive Pills as Primary Prevention for Ovarian Cancer: A Systematic Review and Meta-analysis

@article{Havrilesky2013OralCP,
  title={Oral Contraceptive Pills as Primary Prevention for Ovarian Cancer: A Systematic Review and Meta-analysis},
  author={Laura J. Havrilesky and Patricia G. Moorman and William J. Lowery and Jennifer M Gierisch and Remy R Coeytaux and Rachel Peragallo Urrutia and Michaela A. Dinan and Amanda J. McBroom and Vic Hasselblad and Gillian D. Sanders and Evan R. Myers},
  journal={Obstetrics \& Gynecology},
  year={2013},
  volume={122},
  pages={139–147}
}
OBJECTIVE: To estimate the overall reduction in ovarian cancer risk associated with the use of oral contraceptive pills (OCPs) and whether reduction in risk is affected by specifics of OCP use, such as formulation or duration of use. DATA SOURCES: We searched PubMed, Embase, the Cochrane Database of Systematic Reviews, and ClinicalTrials.gov for studies published from January 1990 to June 2012, with primary analysis of studies published since January 2000. METHODS OF STUDY SELECTION: We… 
Oral contraceptive pills as primary prevention for ovarian cancer: a systematic review and meta-analysis.
TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
There is insufficient evidence to recommend for or against the use of OCs solely for the primary prevention of ovarian cancer, and the harm/benefit ratio was much more favorable when protection against endometrial and colorectal cancers was added.
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TLDR
The present analysis indicates that, after taking into account duration of OC use, the OC protection from ovarian cancer persists for a long time after stopping use.
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TLDR
The relationship between use of oral contraceptives and other contraceptive methods and the risk of ovarian cancer was examined in a combined analysis of 3 hospital‐based case‐control studies in Italy, the United Kingdom, and Greece, suggesting that the protection persists for 15 years or more after cessation of use and may be larger for use at younger age.
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TLDR
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TLDR
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TLDR
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