Oral Contraceptive Pills as Primary Prevention for Ovarian Cancer: A Systematic Review and Meta-analysis
@article{Havrilesky2013OralCP, title={Oral Contraceptive Pills as Primary Prevention for Ovarian Cancer: A Systematic Review and Meta-analysis}, author={Laura J. Havrilesky and Patricia G. Moorman and William J. Lowery and Jennifer M Gierisch and Remy R Coeytaux and Rachel Peragallo Urrutia and Michaela A. Dinan and Amanda J. McBroom and Vic Hasselblad and Gillian D. Sanders and Evan R. Myers}, journal={Obstetrics \& Gynecology}, year={2013}, volume={122}, pages={139–147} }
OBJECTIVE: To estimate the overall reduction in ovarian cancer risk associated with the use of oral contraceptive pills (OCPs) and whether reduction in risk is affected by specifics of OCP use, such as formulation or duration of use. DATA SOURCES: We searched PubMed, Embase, the Cochrane Database of Systematic Reviews, and ClinicalTrials.gov for studies published from January 1990 to June 2012, with primary analysis of studies published since January 2000. METHODS OF STUDY SELECTION: We…
88 Citations
Oral contraceptive pills as primary prevention for ovarian cancer: a systematic review and meta-analysis.
- Biology, MedicineObstetrics and gynecology
- 2013
The authors agree with the authors that oral contraceptive pill use can decrease the risk of developing ovarian cancer, but they believe that further studies still are required.
Intrauterine Device Use and Ovarian Cancer Risk: A Systematic Review and Meta-analysis.
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Intrauterine device use is associated with a reduced incidence of ovarian cancer based on a review of existing retrospective data, and prospective investigation into the role of IUDs in ovarian cancer prevention is limited.
Menopausal Hormone Replacement Therapy and the Risk of Ovarian Cancer: A Meta-Analysis
- Medicine, BiologyFront. Endocrinol.
- 2019
It is suggested that menopausal HRT may increase the risk of ovarian cancer, especially for serous and endometrioid tumors.
Screening and Prevention of Ovarian Cancer
- Medicine
- 2017
Clinicians are recommended to encourage high-risk women who delay or decline risk- reducing surgery to discuss risk-reducing pharmacologic options in order to prevent ovarian cancer progression without elevation of breast cancer risk.
What are the mechanisms of action of the different contraceptive methods to reduce the risk of ovarian cancer?
- MedicineThe European journal of contraception & reproductive health care : the official journal of the European Society of Contraception
- 2020
Combined hormonal contraceptive use is an effective method of chemoprevention for OvCa in the general population and in women with genetic disorders and salpingectomy, better than tubal ligation, should be offered for ovarian/tubal/peritoneal cancer prevention.
The Chemoprevention of Ovarian Cancer: the Need and the Options
- Biology, MedicineCurrent Pharmacology Reports
- 2018
The role of risk assessment in the design of chemoprevention strategies for OvCa is discussed, candidate agents are described, and future directions in this field are assessed.
Beyond the pill: contraception and the prevention of hereditary ovarian cancer
- Medicine, BiologyHereditary cancer in clinical practice
- 2022
There has been a considerable shift in patterns of contraceptive use and the increase in the uptake of non-oral, long-acting, reversible contraception has corresponded to a decline in oral contraceptive pill use, and the impact of these changes on the risk of developing ovarian cancer is not known.
Association of Hormonal Contraceptive Use With Adverse Health Outcomes
- Medicine, PsychologyJAMA network open
- 2022
No associations with adverse outcomes, including cardiovascular and cancer risk, were supported by high-quality evidence, but the association between the use of a levonorgestrel-releasing intrauterine system and reductions in endometrial polyps associated with tamoxifen use was graded as having high- quality evidence.
Interventions to reduce the risk of ovarian and fallopian tube cancer: A European Menopause and Andropause Society Postition Statement.
- MedicineMaturitas
- 2017
Endocrine interventions in women with BRCA1/2 mutations
- MedicineDer Gynäkologe
- 2016
Oral contraceptives seem to slightly increase the breast cancer risk of BRCA1/2 mutation carriers, but they also have a tremendous protective effect against ovarian cancer.
References
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