Oral Administration of Nano-Emulsion Curcumin in Mice Suppresses Inflammatory-Induced NFκB Signaling and Macrophage Migration

@inproceedings{Young2014OralAO,
  title={Oral Administration of Nano-Emulsion Curcumin in Mice Suppresses Inflammatory-Induced NFκB Signaling and Macrophage Migration},
  author={Nicholas A. Young and Michael Bruss and Mark Gardner and William L. Willis and Xiaokui Mo and Giancarlo R. Valiente and Yu Cao and Zhongfa Liu and Wael N. Jarjour and Lai-Chu Wu},
  booktitle={PloS one},
  year={2014}
}
Despite the widespread use of curcumin for centuries in Eastern medicine as an anti-inflammatory agent, its molecular actions and therapeutic viability have only recently been explored. While curcumin does have potential therapeutic efficacy, both solubility and bioavailability must be improved before it can be more successfully translated to clinical care. We have previously reported a novel formulation of nano-emulsion curcumin (NEC) that achieves significantly greater plasma concentrations… CONTINUE READING
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