Optothermal molecule trapping by opposing fluid flow with thermophoretic drift.

@article{Duhr2006OptothermalMT,
  title={Optothermal molecule trapping by opposing fluid flow with thermophoretic drift.},
  author={Stefan Duhr and Dieter Braun},
  journal={Physical review letters},
  year={2006},
  volume={97 3},
  pages={038103}
}
Thermophoresis moves molecules along temperature gradients, typically from hot to cold. We superpose fluid flow with thermophoretic molecule flow under well-defined microfluidic conditions, imaged by fluorescence microscopy. DNA is trapped and accumulated 16-fold in regions where both flows oppose each other. Strong 800-fold accumulation is expected, however, with slow trapping kinetics. The experiment is equally described by a three-dimensional and one-dimensional analytical model. As an… CONTINUE READING
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