Optogenetic identification of striatal projection neuron subtypes during in vivo recordings.

@article{Kravitz2013OptogeneticIO,
  title={Optogenetic identification of striatal projection neuron subtypes during in vivo recordings.},
  author={Alexxai V. Kravitz and Scott F. Owen and Anatol C Kreitzer},
  journal={Brain research},
  year={2013},
  volume={1511},
  pages={21-32}
}
Optogenetics has revolutionized neuroscience over the past several years by allowing researchers to modulate the activity of specific cell types, both in vitro and in vivo. One promising application of optogenetics is to use channelrhodopsin-2 (ChR2) mediated spiking to identify distinct cell types in electrophysiological recordings from awake behaving animals. In this paper, we apply this approach to in vivo recordings of the two major projection cell types in the striatum: the direct- and… CONTINUE READING
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