Optogenetic excitation of central amygdala amplifies and narrows incentive motivation to pursue one reward above another.

@article{Robinson2014OptogeneticEO,
  title={Optogenetic excitation of central amygdala amplifies and narrows incentive motivation to pursue one reward above another.},
  author={Mike J F Robinson and Shelley M Warlow and Kent C. Berridge},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2014},
  volume={34 50},
  pages={16567-80}
}
Choosing one reward above another is important for achieving adaptive life goals. Yet hijacked into excessive intensity in disorders such as addiction, single-minded pursuit becomes maladaptive. Here, we report that optogenetic channelrhodopsin stimulation of neurons in central nucleus of amygdala (CeA), paired with earning a particular sucrose reward in rats, amplified and narrowed incentive motivation to that single reward target. Therefore, CeA rats chose and intensely pursued only the laser… CONTINUE READING
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