Optogenetic approaches to evaluate striatal function in animal models of Parkinson disease.

@article{Parker2016OptogeneticAT,
  title={Optogenetic approaches to evaluate striatal function in animal models of Parkinson disease.},
  author={Krystal L Parker and Youngcho Kim and Stephanie Lorraine Alberico and Eric B Emmons and Nandakumar S. Narayanan},
  journal={Dialogues in clinical neuroscience},
  year={2016},
  volume={18 1},
  pages={
          99-107
        }
}
Optogenetics refers to the ability to control cells that have been genetically modified to express light-sensitive ion channels. The introduction of optogenetic approaches has facilitated the dissection of neural circuits. Optogenetics allows for the precise stimulation and inhibition of specific sets of neurons and their projections with fine temporal specificity. These techniques are ideally suited to investigating neural circuitry underlying motor and cognitive dysfunction in animal models… CONTINUE READING

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