Optogenetic activation of granule cells in the dorsal dentate gyrus enhances dopaminergic neurotransmission in the Nucleus Accumbens

@article{Tritschler2018OptogeneticAO,
  title={Optogenetic activation of granule cells in the dorsal dentate gyrus enhances dopaminergic neurotransmission in the Nucleus Accumbens},
  author={Laurent Tritschler and Mazen A. Kheirbek and Yannick Le Dantec and Indira Mendez-David and Alain Michel Gardier},
  journal={Neuroscience Research},
  year={2018},
  volume={134},
  pages={56-60}
}
The dentate gyrus (DG) has distinct roles along its dorso-ventral axis. In the mouse, we recently demonstrated that dorsal DG (dDG) stimulation enhances exploratory behavior (Kheirbek et al., 2013). Dopamine (DA) release in the Nucleus Accumbens (NAcc), which belongs to the reward system, could be a key target of dDG mediating this motivation-related behavior. Here, an optogenetic stimulation of either ventral (vDG) or dDG granule cells was coupled with NAcc DA release monitoring using in vivo… CONTINUE READING

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Effects of chronic paroxetine treatment on dialysate serotonin in 5 - HT 1 B receptor knockout mice

H. J. Groenewegen, E. Vermeulen-Van der Zee, A. te Kortschot
1987
View 11 Excerpts
Highly Influenced

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