Options for Synthetic DNA Order Screening, Revisited

@inproceedings{DiEuliis2017OptionsFS,
  title={Options for Synthetic DNA Order Screening, Revisited},
  author={Diane DiEuliis and Sarah Rosemary Carter and Gigi Kwik Gronvall},
  booktitle={mSphere},
  year={2017}
}
Gene synthesis providers affiliated with the International Gene Synthesis Consortium (IGSC) voluntarily screen double-stranded DNA (dsDNA) synthesis orders over 200 bp to check for matches to regulated pathogens and to screen customers. Questions have been raised, however, about the continuing feasibility and effectiveness of screening. There are technical challenges (e.g., oligonucleotides and tracts of DNA less than 200 bp are not screened) and corporate challenges (e.g., the costs of… CONTINUE READING

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