Optimizing syngeneic orthotopic murine bladder cancer (MB49).

@article{Gnther1999OptimizingSO,
  title={Optimizing syngeneic orthotopic murine bladder cancer (MB49).},
  author={J{\"o}rg G{\"u}nther and Andreas Jurczok and Tina Wulf and Sven Brandau and Irina Deinert and Dieter Jocham and Andreas Boehle},
  journal={Cancer research},
  year={1999},
  volume={59 12},
  pages={2834-7}
}
The syngeneic orthotopic murine bladder cancer model MB49 is hampered by unreliable tumor implantation. We optimized this model by a simple modification of the standard implantation technique in three groups of mice. Fifty thousand (group I), 20,000 (group II), or 10,000 (group III) tumor cells were implanted into cauterized bladders by transurethral instillation, and dwell time was prolonged to 3 h. Tumor take, survival, and bladder weights were determined as outcome variables. To verify… CONTINUE READING
49 Citations
20 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 49 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 20 references

A model of orthotopic murine bladder (MBT-2) tumor implants

  • F. Jiang, Zhou, X-M
  • Urol. Res.,
  • 1997
1 Excerpt

Similar Papers

Loading similar papers…