Optimizing retinal ganglion cell responses to high-frequency electrical stimulation strategies for preferential neuronal excitation

Abstract

A retinal ganglion cell (RGC) model based on accurate biophysics and detailed representations of cell morphologies was used to understand how these cells respond to electrical stimulation over a wide range of frequencies, spanning 50-2000 pulses per second (PPS). Our modeling results and associated in vitro data both suggest the usefulness of high… (More)

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