Optimizing isolation culture and freezing methods to preserve Wharton's jelly's mesenchymal stem cell (MSC) properties: an MSC banking protocol validation for the Hellenic Cord Blood Bank.

@article{Chatzistamatiou2014OptimizingIC,
  title={Optimizing isolation culture and freezing methods to preserve Wharton's jelly's mesenchymal stem cell (MSC) properties: an MSC banking protocol validation for the Hellenic Cord Blood Bank.},
  author={Theofanis Chatzistamatiou and Andreas C Papassavas and Efstathios Michalopoulos and Christos Gamaloutsos and Panagiotis Mallis and Ioanna Gontika and Effrosyni Panagouli and Stauros Koussoulakos and Catherine G Stavropoulos-Giokas},
  journal={Transfusion},
  year={2014},
  volume={54 12},
  pages={3108-20}
}
BACKGROUND Mesenchymal stem or stromal cells (MSCs) are a heterogeneous population that can be isolated from many tissues including umbilical cord Wharton's jelly (UC-WJ). Although initially limited in studies such as a hematopoietic stem cell transplantation adjuvant, an increasing number of clinical trials consider MSCs as a potential anti-inflammatory or a regenerative medicine agent. It has been proposed that creating a repository of MSCs would increase their availability for clinical… CONTINUE READING
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