Optimizing information flow in small genetic networks.

@article{Tkaik2009OptimizingIF,
  title={Optimizing information flow in small genetic networks.},
  author={Ga{\vs}per Tka{\vc}ik and Aleksandra M. Walczak and William Bialek},
  journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
  year={2009},
  volume={80 3 Pt 1},
  pages={
          031920
        }
}
  • Gašper Tkačik, Aleksandra M. Walczak, William Bialek
  • Published in
    Physical review. E…
    2009
  • Physics, Computer Science, Biology, Medicine
  • In order to survive, reproduce, and (in multicellular organisms) differentiate, cells must control the concentrations of the myriad different proteins that are encoded in the genome. The precision of this control is limited by the inevitable randomness of individual molecular events. Here we explore how cells can maximize their control power in the presence of these physical limits; formally, we solve the theoretical problem of maximizing the information transferred from inputs to outputs when… CONTINUE READING

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