Optimizing chronic transfusion therapy for survivors of hemoglobin Barts hydrops fetalis.

@article{Amid2016OptimizingCT,
  title={Optimizing chronic transfusion therapy for survivors of hemoglobin Barts hydrops fetalis.},
  author={Ali Amid and Shiyi Chen and William Brien and Melanie Kirby-Allen and Isaac Odame},
  journal={Blood},
  year={2016},
  volume={127 9},
  pages={
          1208-11
        }
}
Hemoglobin Barts hydrops fetalis (homozygous a-thalassemia) results from deletion of all 4 a-globin genes. It was previously considered a universally fatal condition; however,with recent advances in prenatal care and the availability of intrauterine blood transfusions, an increasing number of patients are now surviving into adulthood. Similar to patients with transfusion-dependent thalassemia due to b-thalassemia (TDT-b), these patients require lifelong and regular transfusions, as the option… CONTINUE READING
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