Optimizing cardiac resynchronization therapy to minimize ATP consumption heterogeneity throughout the left ventricle: a simulation analysis using a canine heart failure model.

@article{Hu2014OptimizingCR,
  title={Optimizing cardiac resynchronization therapy to minimize ATP consumption heterogeneity throughout the left ventricle: a simulation analysis using a canine heart failure model.},
  author={Yuxuan Hu and Viatcheslav Gurev and Jason L Constantino and Natalia A. Trayanova},
  journal={Heart rhythm},
  year={2014},
  volume={11 6},
  pages={1063-9}
}
BACKGROUND Cardiac resynchronization therapy (CRT) has been demonstrated to lead to restoration of oxygen consumption homogeneity throughout the left ventricle (LV), which is important for long-term reverse remodeling of the ventricles. However, research has focused exclusively on identifying the LV pacing sites that led to acute hemodynamic improvements. It remains unclear whether there exist LV pacing sites that could both improve the hemodynamics and result in ATP consumption homogeneity… CONTINUE READING