Optimizing antimicrobial therapy in sepsis and septic shock.

  title={Optimizing antimicrobial therapy in sepsis and septic shock.},
  author={Anand Kumar},
  journal={Critical care nursing clinics of North America},
  volume={23 1},
Every patient with sepsis and septic shock must be evaluated thoroughly at presentation before the initiation of antibiotic therapy. However, in most situations, an abridged initial assessment focusing on critical diagnostic and management planning elements is sufficient. Intravenous antibiotics should be administered as early as possible, and always within the first hour of recognizing severe sepsis and septic shock. Broad-spectrum antibiotics must be selected with one or more agents active… CONTINUE READING
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