Optimizing a proteomics platform for urine biomarker discovery.

Abstract

Biomarker discovery approaches in urine have been hindered by concerns for reproducibility and inadequate standardization of proteomics protocols. In this study, we describe an optimized quantitative proteomics strategy for urine biomarker discovery, which is applicable to fresh or long frozen samples. We used urine from healthy controls to standardize… (More)
DOI: 10.1074/mcp.M110.000992

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6 Figures and Tables