Optimizing Anti-TNF-α Therapy: Serum Levels of Infliximab and Adalimumab Are Associated With Mucosal Healing in Patients With Inflammatory Bowel Diseases.

@article{Ungar2016OptimizingAT,
  title={Optimizing Anti-TNF-α Therapy: Serum Levels of Infliximab and Adalimumab Are Associated With Mucosal Healing in Patients With Inflammatory Bowel Diseases.},
  author={Bella Ungar and Idan Levy and Yarden Yavne and Miri Yavzori and Orit Picard and Ella Fudim and Ronen Loebstein and Yehuda Chowers and R. Eliakim and Uri Kopylov and Shomron Ben-Horin},
  journal={Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association},
  year={2016},
  volume={14 4},
  pages={
          550-557.e2
        }
}
  • Bella Ungar, Idan Levy, +8 authors Shomron Ben-Horin
  • Published in
    Clinical gastroenterology and…
    2016
  • Medicine
  • BACKGROUND & AIMS It is not clear what serum levels of anti-tumor necrosis factor are associated with reduced intestinal inflammation in patients with inflammatory bowel disease (IBD). We aimed to identify serum levels of infliximab and adalimumab associated with mucosal healing in patients with IBD and to evaluate the putative gain in control of inflammation by incremental increases in drug levels. METHODS We performed a retrospective cross-sectional study of 145 patients with IBD treated… CONTINUE READING

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