Optimized sample preparation for MALDI mass spectrometry analysis of protected synthetic peptides.

Abstract

The recent development and commercialization of Fuzeon (enfuvirtide) demonstrated that a convergent strategy comprised of both solid- and solution-phase synthetic methodologies presents a viable route for peptide manufacturing on a multi-ton scale. In this strategy, the target sequence is prepared by stepwise solid-phase synthesis of protected peptide… (More)
DOI: 10.1016/j.jasms.2008.01.010

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Cite this paper

@article{Schaiberger2008OptimizedSP, title={Optimized sample preparation for MALDI mass spectrometry analysis of protected synthetic peptides.}, author={Audrey M Schaiberger and Jason A Moss}, journal={Journal of the American Society for Mass Spectrometry}, year={2008}, volume={19 4}, pages={614-9} }