Optimized luciferase assay for cell-penetrating peptide-mediated delivery of short oligonucleotides.

@article{Helmfors2015OptimizedLA,
  title={Optimized luciferase assay for cell-penetrating peptide-mediated delivery of short oligonucleotides.},
  author={Henrik Helmfors and Jonas Eriksson and {\"U}lo Langel},
  journal={Analytical biochemistry},
  year={2015},
  volume={484},
  pages={136-42}
}
An improved assay for screening for the intracellular delivery efficacy of short oligonucleotides using cell-penetrating peptides is suggested. This assay is an improvement over previous assays that use luciferase reporters for cell-penetrating peptides because it has been scaled up from a 24-well format to a 96-well format and no longer relies on a… CONTINUE READING