Optimized exosome isolation protocol for cell culture supernatant and human plasma

@inproceedings{Lobb2015OptimizedEI,
  title={Optimized exosome isolation protocol for cell culture supernatant and human plasma},
  author={Richard J. Lobb and Melanie Becker and Shu Wen Wen and Christina S. F. Wong and A P Wiegmans and Antoine Leimgruber and Andreas M{\"o}ller},
  booktitle={Journal of extracellular vesicles},
  year={2015}
}
Extracellular vesicles represent a rich source of novel biomarkers in the diagnosis and prognosis of disease. However, there is currently limited information elucidating the most efficient methods for obtaining high yields of pure exosomes, a subset of extracellular vesicles, from cell culture supernatant and complex biological fluids such as plasma. To this end, we comprehensively characterize a variety of exosome isolation protocols for their efficiency, yield and purity of isolated exosomes… CONTINUE READING
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