Optimized and validated spectrophotometric methods for the determination of nicorandil in drug formulations and biological fluids.

Abstract

Two simple, sensitive and economical spectrophotometric methods have been developed for the determination of nicorandil in drug formulations and biological fluids. Method A is based on the reaction of the drug with brucine-sulphanilic acid reagent in sulphuric acid medium producing a yellow-coloured product, which absorbs maximally at 410 nm. Method B… (More)

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