Optimized Enzymatic Synthesis of Hesperidin Fatty Acid Esters in a Two-Phase System Containing Ionic Liquid

@inproceedings{Arajo2011OptimizedES,
  title={Optimized Enzymatic Synthesis of Hesperidin Fatty Acid Esters in a Two-Phase System Containing Ionic Liquid},
  author={Maria Elisa Melo Branco de Ara{\'u}jo and Fabiano Jares Contesini and Yollanda Edwirges Moreira Franco and Alexandra C.H. Frankland Sawaya and Thiago Grando Alberto and Nat{\'a}lia Dalfr{\'e} and Patr{\'i}cia de Oliveira Carvalho},
  booktitle={Molecules},
  year={2011}
}
Response surface methodology (RSM) based on a five-level, three-variable central composite design (CCD) was employed for modeling and optimizing the conversion yield of the enzymatic acylation of hesperidin with decanoic acid using immobilized Candida antarctica lipase B (CALB) in a two-phase system containing [bmim]BF(4). The three variables studied (molar ratio of hesperidin to decanoic acid, [bmim]BF(4)/acetone ratio and lipase concentration) significantly affected the conversion yield of… CONTINUE READING

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