Optimized, highly efficient transfer of foreign genes into newborn mouse hearts in vivo.

Abstract

Expression of foreign genes in vivo is a standard method to disclose functions of specific genes and to alter physiological conditions in distinct cell types and tissues. Virus-mediated gene transfer has proved to be a valuable tool for directed gene expression in vivo complementary to transgenic approaches. However, several problems associated with routes… (More)

Topics

  • Presentations referencing similar topics