Optimization studies on development and evaluation of papain-based in situ gelling system for chemomechanical caries removal.

@article{Tripathi2014OptimizationSO,
  title={Optimization studies on development and evaluation of papain-based in situ gelling system for chemomechanical caries removal.},
  author={Ravi Shankar Tripathi and Kamla Pathak},
  journal={Pharmaceutical development and technology},
  year={2014},
  pages={1-11}
}
Abstract Context: Chemomechanical caries removal is a non-invasive technique that eliminates infected dentine via a chemical agent. Papain, owing to its proteolytic nature causes disruption of degraded collagen fibrils that helps easy removal of the caries and has both bacteriostatic and bactericidal action. Objective: The objective of the present work was to formulate and evaluate papain-based in situ gelling system for chemomechanical caries removal, based on the concept of pH-triggered in… CONTINUE READING