Optimization of the isolation and expansion method of human mediastinal–adipose tissue derived mesenchymal stem cells with virally inactivated GMP-grade platelet lysate

@article{Siciliano2013OptimizationOT,
  title={Optimization of the isolation and expansion method of human mediastinal–adipose tissue derived mesenchymal stem cells with virally inactivated GMP-grade platelet lysate},
  author={Camilla Siciliano and Mohsen Ibrahim and Gaia Scafetta and Chiara Napoletano and Giorgio Mangino and L Pierelli and Giacomo Frati and Elena De Falco},
  journal={Cytotechnology},
  year={2013},
  volume={67},
  pages={165-174}
}
Mesenchymal stem cells (MSCs) are adult multipotent cells currently employed in several clinical trials due to their immunomodulating, angiogenic and repairing features. The adipose tissue is certainly considered an eligible source of MSCs. Recently, putative adipose tissue derived MSCs (ADMSCs) have been isolated from the mediastinal depots. However, very little is known about the properties, the function and the potential of human mediastinal ADMSCs (hmADMSCs). However, the lack of… CONTINUE READING