Optimization of the fractionated irradiation scheme considering physical doses to tumor and organ at risk based on dose-volume histograms.

@article{Sugano2015OptimizationOT,
  title={Optimization of the fractionated irradiation scheme considering physical doses to tumor and organ at risk based on dose-volume histograms.},
  author={Yasutaka Sugano and Masahiro Mizuta and Seishin Takao and Hiroki Shirato and Kenneth Sutherland and Hiroyuki Date},
  journal={Medical physics},
  year={2015},
  volume={42 11},
  pages={
          6203-10
        }
}
PURPOSE Radiotherapy of solid tumors has been performed with various fractionation regimens such as multi- and hypofractionations. However, the ability to optimize the fractionation regimen considering the physical dose distribution remains insufficient. This study aims to optimize the fractionation regimen, in which the authors propose a graphical method for selecting the optimal number of fractions (n) and dose per fraction (d) based on dose-volume histograms for tumor and normal tissues of… 
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11 Citations

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Citation Type

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