Optimization of the expression of the HIV fusion inhibitor cyanovirin-N from the tobacco plastid genome.

@article{Elghabi2011OptimizationOT,
  title={Optimization of the expression of the HIV fusion inhibitor cyanovirin-N from the tobacco plastid genome.},
  author={Zouhair Elghabi and Daniel Karcher and Fei Zhou and Stephanie Ruf and Ralph Bock},
  journal={Plant biotechnology journal},
  year={2011},
  volume={9 5},
  pages={599-608}
}
Plants with transgenic plastid (chloroplast) genomes represent a promising production platform in molecular farming, mainly because of the plastids' potential to accumulate foreign proteins to very high levels and the increased biosafety conferred by the maternal mode of plastid inheritance. Although some transgenes can be expressed to extraordinarily high levels, the expression of others has been unsuccessful. Lack of detectable transgene expression is usually attributable to either RNA… CONTINUE READING

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