Optimization of temperature-programmed gas chromatographic separations , II : Off-line Simplex optimization and column selection

@inproceedings{Snijders2002OptimizationOT,
  title={Optimization of temperature-programmed gas chromatographic separations , II : Off-line Simplex optimization and column selection},
  author={Henri Snijders and H. Jan\ssen and Carel A. Cramers},
  year={2002}
}
In this work a method is described which allows off-line optimization of temperature-programmed GC separations. The method is based on a new numerical method that allows the off-line prediction of retention times and peak widths of a mixture containing components with known identities in capillary GC. In the present work we apply this method for off-line optimization of singleand multi-ramp temperature-programmed GC separations. First, it will be shown how the numerical methods are incorporated… CONTINUE READING

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