Optimization of scaffold design for bone tissue engineering: A computational and experimental study.

@article{Dias2014OptimizationOS,
  title={Optimization of scaffold design for bone tissue engineering: A computational and experimental study.},
  author={Marta R. Dias and Jos{\'e} Miranda Guedes and Colleen L. Flanagan and Scott J. Hollister and Paulo R. Fernandes},
  journal={Medical engineering & physics},
  year={2014},
  volume={36 4},
  pages={448-57}
}
In bone tissue engineering, the scaffold has not only to allow the diffusion of cells, nutrients and oxygen but also provide adequate mechanical support. One way to ensure the scaffold has the right properties is to use computational tools to design such a scaffold coupled with additive manufacturing to build the scaffolds to the resulting optimized design specifications. In this study a topology optimization algorithm is proposed as a technique to design scaffolds that meet specific… CONTINUE READING