Optimization of methods for quantification of rCBF using high-resolution [¹⁵O]H₂O PET images.

@article{Walker2012OptimizationOM,
  title={Optimization of methods for quantification of rCBF using high-resolution [¹⁵O]H₂O PET images.},
  author={Matthew D. Walker and Maria Feldmann and Julian C. Matthews and Jose M. Anton-Rodriguez and Shyh-Jen Wang and Matthias J. Koepp and M-C Asselin},
  journal={Physics in medicine and biology},
  year={2012},
  volume={57 8},
  pages={2251-71}
}
This study aimed to derive accurate estimates of regional cerebral blood flow (rCBF) from noisy dynamic [¹⁵O]H₂O PET images acquired on the high-resolution research tomograph, while retaining as much as possible the high spatial resolution of this brain scanner (2-3 mm) in parametric maps of rCBF. The PET autoradiographic method and generalized linear least-squares (GLLS), with fixed or extended to include spatially variable estimates of the dispersion of the measured input function, were… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…