Optimization of methods for aspartate aminotransferase and alanine aminotransferase.

@article{Bergmeyer1978OptimizationOM,
  title={Optimization of methods for aspartate aminotransferase and alanine aminotransferase.},
  author={Hans Ulrich Bergmeyer and P. Scheibe and August Wilhelm Wahlefeld},
  journal={Clinical chemistry},
  year={1978},
  volume={24 1},
  pages={
          58-73
        }
}
  • Hans Ulrich Bergmeyer, P. Scheibe, August Wilhelm Wahlefeld
  • Published in Clinical chemistry 1978
  • Medicine, Chemistry
  • Conditions for accurate measurement of catalytic activity of aspartate aminotransferase and alanine aminotransferase in human serum have been reinvestigated. The basic variables (kind of buffer, buffer concentration, pH, ion effects, and the influence of pyridoxal-5-phosphate) can now be considered optimized. On this basis, the kinetic parameters of both aminotransferases were determined, i.e., Michaelis and inhibitor constants for substrates and reaction products. With a mathematical approach… CONTINUE READING

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