Optimization of medium constituents for ε-poly-L-lysine fermentation with response surface methodology.

@article{Zong2010OptimizationOM,
  title={Optimization of medium constituents for $\epsilon$-poly-L-lysine fermentation with response surface methodology.},
  author={H. Zong and Yibo He and Y. Zhan and Juan Du and Fengqin Feng and Duo Li},
  journal={Journal of food science},
  year={2010},
  volume={75 9},
  pages={
          M552-6
        }
}
ε-Poly-L-lysine (ε-PL) is a novel food biopreservative with broad antimicrobial activity. In the present study, single-factor experiments were applied to screen optimal carbon and nitrogen sources that affect the yield of a ε-PL-producing strain, Streptomyces violaceusniger, which was obtained in our laboratory recently. Box-Behnken design and response surface methodology (RSM) were adopted to derive a statistical model for optimizing the composition of the fermentation medium. The results… Expand
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