Optimization of low-cost medium for very high gravity ethanol fermentations by Saccharomyces cerevisiae using statistical experimental designs.

@article{Pereira2010OptimizationOL,
  title={Optimization of low-cost medium for very high gravity ethanol fermentations by Saccharomyces cerevisiae using statistical experimental designs.},
  author={Francisco Baptista Pereira and Pedro Guimaraes and Jos{\'e} Ant{\'o}nio Couto Teixeira and Luc{\'i}lia Domingues},
  journal={Bioresource technology},
  year={2010},
  volume={101 20},
  pages={7856-63}
}
Statistical experimental designs were used to develop a medium based on corn steep liquor (CSL) and other low-cost nutrient sources for high-performance very high gravity (VHG) ethanol fermentations by Saccharomyces cerevisiae. The critical nutrients were initially selected according to a Plackett-Burman design and the optimized medium composition (44.3 g/L CSL; 2.3 g/L urea; 3.8 g/L MgSO₄·7H₂O; 0.03 g/L CuSO₄·5H₂O) for maximum ethanol production by the laboratory strain CEN.PK 113-7D was… CONTINUE READING

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