Optimization of lactic acid production by immobilized Lactococcus lactis IO-1

  title={Optimization of lactic acid production by immobilized Lactococcus lactis IO-1},
  author={Sarote Sirisansaneeyakul and Tiyaporn Luangpipat and Wirat Vanichsriratana and Thongchai Srinophakun and Henry H. G. Chen and Yusuf Chisti},
  journal={Journal of Industrial Microbiology & Biotechnology},
Production of lactic acid from glucose by immobilized cells of Lactococcus lactis IO-1 was investigated using cells that had been immobilized by either entrapment in beads of alginate or encapsulation in microcapsules of alginate membrane. The fermentation process was optimized in shake flasks using the Taguchi method and then further assessed in a production bioreactor. The bioreactor consisted of a packed bed of immobilized cells and its operation involved recycling of the broth through the… CONTINUE READING


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