Optimization of fully aligned bioactive electrospun fibers for “in vitro” nerve guidance

@article{Cirillo2014OptimizationOF,
  title={Optimization of fully aligned bioactive electrospun fibers for “in vitro” nerve guidance},
  author={V. Cirillo and V. Guarino and M. {\'A}lvarez-P{\'e}rez and M. Marrese and L. Ambrosio},
  journal={Journal of Materials Science: Materials in Medicine},
  year={2014},
  volume={25},
  pages={2323-2332}
}
Complex architecture of natural tissues such as nerves requires the use of multifunctional scaffolds with peculiar topological and biochemical signals able to address cell behavior towards specific events at the cellular (microscale) and macromolecular (nanoscale) level. In this context, the electrospinning technique is useful to generate fiber assemblies having peculiar fiber diameters at the nanoscale and patterned by unidirectional ways, to facilitate neurite extension via contact guidance… Expand
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