Optimization of conditions for the liquid chromatographic-electrospray lonization-mass spectrometric analysis of amnesic shellfish poisoning toxins

  title={Optimization of conditions for the liquid chromatographic-electrospray lonization-mass spectrometric analysis of amnesic shellfish poisoning toxins},
  author={N. Pi{\~n}eiro and E. Vaquero and J. M. Le{\~a}o and A. Gogo-Mart{\'i}nez and J. Rodr{\'i}guez V{\'a}zquez},
SummaryIn this paper we report results obtained from analysis of domoic acid and its analogues, toxins responsible for incidents of amnesic shellfish poisoning (ASP) in several places world-wide, by use of liquid chromatography coupled with electrospray ionization mass spectrometry. Different chromatographic and mass spectrometry conditions were evaluated with the aim of achieving the best chromatographic performance combined with the optimum mass spectrometric response. From the results… Expand
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