Optimization of conditions for the liquid chromatographic-electrospray lonization-mass spectrometric analysis of amnesic shellfish poisoning toxins

@article{Pieiro2001OptimizationOC,
  title={Optimization of conditions for the liquid chromatographic-electrospray lonization-mass spectrometric analysis of amnesic shellfish poisoning toxins},
  author={N Pi{\~n}eiro and Estela Vaquero and Jos{\'e} Manuel Le{\~a}o and A. Gogo-Mart{\'i}nez and J.F. Rodr{\'i}guez V{\'a}zquez},
  journal={Chromatographia},
  year={2001},
  volume={53},
  pages={S231-S235}
}
SummaryIn this paper we report results obtained from analysis of domoic acid and its analogues, toxins responsible for incidents of amnesic shellfish poisoning (ASP) in several places world-wide, by use of liquid chromatography coupled with electrospray ionization mass spectrometry. Different chromatographic and mass spectrometry conditions were evaluated with the aim of achieving the best chromatographic performance combined with the optimum mass spectrometric response. From the results… 

Mass spectrometric detection in chromatography. Trends and perspectives.

The newest results in the use of miscellaneous mass spectrometric detection methods in various chromatographic techniques are compiled and critically evaluated. Examples of application in clinical

Marine biotoxins in shellfish – Domoic acid 1 Scientific Opinion of the Panel on Contaminants in the Food Chain ( Question No EFSA-Q-2006-065 H ) Adopted on 2 July 2009

Domoic acid (DA) and its isomers are marine biotoxins causing amnesic shellfish poisoning (ASP) in humans. Symptoms of ASP include gastrointestinal symptoms (vomiting, diarrhoea or abdominal cramps)

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