Optimization of bone-tissue engineering in goats.

  title={Optimization of bone-tissue engineering in goats.},
  author={Moyo Chikondi Kruyt and Wouter J. A. Dhert and Cumhur F. Oner and Clemens A van Blitterswijk and Abraham J. Verbout and Joost D. de Bruijn},
  journal={Journal of biomedical materials research. Part B, Applied biomaterials},
  volume={69 2},
Successful bone-tissue engineering (TE) has been reported for various strategies to combine cells with a porous scaffold. In particular, the period after seeding until implantation of the constructs may vary between hours and several weeks. Differences between these strategies can be reduced to (a) the presence of extracellular matrix, (b) the differentiation status of the cells, and (c) the presence of residual potentially immunogenic serum proteins. These parameters are investigated in two… CONTINUE READING


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