Optimization of anesthesia protocol for resting-state fMRI in mice based on differential effects of anesthetics on functional connectivity patterns

@article{Grandjean2014OptimizationOA,
  title={Optimization of anesthesia protocol for resting-state fMRI in mice based on differential effects of anesthetics on functional connectivity patterns},
  author={Joanes Grandjean and Aileen Schroeter and Imene Batata and Markus Rudin},
  journal={NeuroImage},
  year={2014},
  volume={102 Pt 2},
  pages={838-47}
}
Resting state-fMRI (rs-fMRI) in mice allows studying mechanisms underlying functional connectivity (FC) as well as alterations of FC occurring in murine models of neurological diseases. Mouse fMRI experiments are typically carried out under anesthesia to minimize animal movement and potential distress during examination. Yet, anesthesia inevitably affects FC patterns. Such effects have to be understood for proper interpretation of data. We have compared the influence of four commonly used… CONTINUE READING
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CBV-weighted resting-state networks in the mouse brain

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