Optimization of an air–liquid interface exposure system for assessing toxicity of airborne nanoparticles

@inproceedings{Latvala2016OptimizationOA,
  title={Optimization of an air–liquid interface exposure system for assessing toxicity of airborne nanoparticles},
  author={Siiri Latvala and Jonas Hedberg and Lennart M{\"o}ller and Inger Odnevall Wallinder and Hanna L Karlsson and Karine Elihn},
  booktitle={Journal of applied toxicology : JAT},
  year={2016}
}
The use of refined toxicological methods is currently needed for characterizing the risks of airborne nanoparticles (NPs) to human health. To mimic pulmonary exposure, we have developed an air-liquid interface (ALI) exposure system for direct deposition of airborne NPs on to lung cell cultures. Compared to traditional submerged systems, this allows more realistic exposure conditions for characterizing toxicological effects induced by airborne NPs. The purpose of this study was to investigate… CONTINUE READING
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