Optimization of a rapid microwave-assisted extraction method for the simultaneous determination of opiates, cocaine and their metabolites in human hair.

@article{Fernndez2009OptimizationOA,
  title={Optimization of a rapid microwave-assisted extraction method for the simultaneous determination of opiates, cocaine and their metabolites in human hair.},
  author={Purificaci{\'o}n Fern{\'a}ndez and Marta Lago and Rosa Antonia Lorenzo and Antonia Mar{\'i}a Carro and Ana Mar{\'i}a Bermejo and Mar{\'i}a Jes{\'u}s Tabernero},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  year={2009},
  volume={877 18-19},
  pages={1743-50}
}
A rapid and cleanup-free microwave-assisted extraction (MAE) method is proposed for the simultaneous extraction of six illegal drugs of abuse - cocaine, benzoylecgonine (BZE), cocaethylene (CCE), morphine, 6-monoacethylmorphine (6AM) and codeine - from human hair samples. The analytes were determined using high performance liquid chromatography (HPLC) with photodiode array UV detection. The influence of several variables on the efficiency of the MAE procedure was investigated in detail by a… CONTINUE READING
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