Optimization of PSA screening policies: a comparison of the patient and societal perspectives.

@article{Zhang2012OptimizationOP,
  title={Optimization of PSA screening policies: a comparison of the patient and societal perspectives.},
  author={Jingyu Zhang and Brian T. Denton and Hari Balasubramanian and Nilay D. Shah and Brant A. Inman},
  journal={Medical decision making : an international journal of the Society for Medical Decision Making},
  year={2012},
  volume={32 2},
  pages={
          337-49
        }
}
OBJECTIVE To estimate the benefit of PSA-based screening for prostate cancer from the patient and societal perspectives. METHOD A partially observable Markov decision process model was used to optimize PSA screening decisions. Age-specific prostate cancer incidence rates and the mortality rates from prostate cancer and competing causes were considered. The model trades off the potential benefit of early detection with the cost of screening and loss of patient quality of life due to screening… CONTINUE READING

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