Optimization of PCR based detection of human papillomavirus DNA from urine specimens.

@article{Brinkman2004OptimizationOP,
  title={Optimization of PCR based detection of human papillomavirus DNA from urine specimens.},
  author={Joeli A Brinkman and Meliha Z Rahmani and W Elizabeth Jones and Anil K Chaturvedi and Michael E. Hagensee},
  journal={Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology},
  year={2004},
  volume={29 4},
  pages={230-40}
}
BACKGROUND Human papillomavirus (HPV) causes cervical cancer. Current screening requires a yearly pelvic exam and Pap smear. However, these procedures are impractical for screening all women at risk for disease. Urine sampling has been successfully utilized to screen for Chlamydia trachomatis (CT) and Neisseria gonorrhoreae (NG) infections and has been considered for HPV DNA detection by several investigators. However, no study to date has been performed to specifically optimize HPV detection… CONTINUE READING

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