Optimization of Olive Oil-Based Nanoemulsion Preparation for Intravenous Drug Delivery.

@article{Karami2019OptimizationOO,
  title={Optimization of Olive Oil-Based Nanoemulsion Preparation for Intravenous Drug Delivery.},
  author={Zahra Karami and Maryam Khoshkam and Mehrdad Hamidi},
  journal={Drug research},
  year={2019},
  volume={69 5},
  pages={
          256-264
        }
}
A seven-factor Box-Behnken design was used for the optimized development of an olive oil-based nanoemulsion (NE) intended for intravenous drug delivery. The independent variables of olive oil concentration, tween 80 concentration, span 80 concentration, rate of adding of oil in aqueous phase, homogenization speed, homogenization time, and preparation temperature, were used as inputs of the factorial design. The response variables were mean droplet diameter, zeta potential (ZP), and… CONTINUE READING
1
Twitter Mention

References

Publications referenced by this paper.
SHOWING 1-10 OF 26 REFERENCES

Nanoemulsion: Concepts, development and applications in drug delivery

  • Journal of controlled release : official journal of the Controlled Release Society
  • 2017
VIEW 1 EXCERPT

Drug delivery and drug targeting with parenteral lipid nanoemulsions - A review.

  • Journal of controlled release : official journal of the Controlled Release Society
  • 2016
VIEW 1 EXCERPT