Optimization and scale-up of Wharton's jelly-derived mesenchymal stem cells for clinical applications.

@article{Nekanti2010OptimizationAS,
  title={Optimization and scale-up of Wharton's jelly-derived mesenchymal stem cells for clinical applications.},
  author={Usha Nekanti and Lipsa Mohanty and Parvathy Venugopal and Sudha Balasubramanian and Satish Mahadeorao Totey and Malancha Ta},
  journal={Stem cell research},
  year={2010},
  volume={5 3},
  pages={
          244-54
        }
}
MSCs are promising candidates for stem cell therapy and regenerative medicine. Umbilical cord is the easiest obtainable biological source of MSCs and the Wharton's jelly of the umbilical cord is a rich source of fetus-derived stem cells. However, the use of MSCs for therapeutic application is based on their subsequent large-scale in vitro expansion. A fast and efficient protocol for generation of large quantities of MSCs is required to meet the clinical demand and biomedical research needs… CONTINUE READING
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