Optimization and Performance Assessment of the Chorion-Off [Dechorinated] Zebrafish Developmental Toxicity Assay.

@article{PanzicaKelly2015OptimizationAP,
  title={Optimization and Performance Assessment of the Chorion-Off [Dechorinated] Zebrafish Developmental Toxicity Assay.},
  author={Julieta M Panzica-Kelly and Cindy X Zhang and Karen A Augustine-Rauch},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2015},
  volume={146 1},
  pages={127-34}
}
The Dechorinated Zebrafish Embryo Developmental toxicity assay was originally developed from a training set of 31 compounds and reported to be 87% concordant with in vivo teratogenicity data (Brannen, K. C., Panzica-Kelly, J. M., Danberry, T. L., and Augustine-Rauch, K. A. (2010). Development of a zebrafish embryo teratogenicity assay and quantitative prediction model. Birth Defects Res. 89, 66-77.). The assay includes scoring larva treated in a concentration range for malformations of specific… CONTINUE READING
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Development of a screening assay to identify teratogenic and embryotoxic chemicals using the zebrafish

  • I. W. Selderslaghs, A. R. Van Rompay, W. De Coen, H. E. Witters
  • embryo. Reprod. Toxicol
  • 2009
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