The purpose of the study was to explore the relationships between optimism, well-being, resilience and perceived stress among undergraduates. The sample consists of 181 students (77 male and 104 female) within age range of 18 to 25 years. Perceived Stress Scale (PSS, Cohen, Kamarck, & Mermelstein, 1983), Warwick Edinburgh Mental Well-being Scale (WEMWBS, Tennant et al., 2007), Optimism/Pessimism Instrument (OPI, Dember, Martin, Hummer, Howe, & Melton, 1989) and Resilience Scale (Wagnild & Young, 1993) were administered to all the respondents. The data were analysed by using descriptive statistics i.e. mean and SD, Pearson product moment correlation and step wise multiple regression. The results revealed optimism to have a significant positive relationship with well-being and resilience. Well-being was found to be significantly positively correlated with resilience. The step wise regression analysis found that resilience is a predictor of well-being.